Imaging of psoriatic nail disease pre and post anti-TNF therapy shows persistent subclinical inflammation despite good clinical response
نویسندگان
چکیده
Background In psoriatic arthritis (PsA), nail disease is intimately linked to the presence of DIP joint enthesitis and arthritis. Nail disease has been shown in clinical trials to respond to treatment with TNF inhibitors. We used high resolution MRI to assess whether improvements in psoriasis-related nail disease correlated to improvements in associated DIP joint enthesitis, osteitis and synovitis during TNF inhibitor therapy.
منابع مشابه
MRI of psoriatic nail disease pre- and post-TNF inhibitor therapy shows persistent subclinical inflammation after 6 months despite good clinical response
Nail involvement is part of the clinical spectrum of psoriatic disease and is microanatomically associated with distal interphalangeal joint (DIPJ) entheses. Tumour necrosis factor (TNF) inhibitors have shown efficacy for psoriasis, arthritis, enthesitis, dactylitis and nail disease. Given the intimate links between psoriatic arthritis (PsA) and nail disease, it might be expected that nail dise...
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